PLoS Pathog (2011) 7:e1002250.10.1371/journal.ppat.1002250 42 SalzanoSChecconiPHanschmannEMLilligCHBowlerLDChanPet alLinkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal
this was followed by daily oral administration of 300 mg of L-glutathione for the following 4 months
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Others utilized in vitro exposure of gametes to peptide-supplemented media and found similar benefits, which aid in decoupling direct gamete effects from whole-animal systemic changes
Erten OU, Ensari TGA, Dilbaz B, Cakiroglu H, Altinbas SK, Caydere M, et al